Overview of 3D Bioprinting of tissues and organs – A Review
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Published
Sep 20, 2021
Manjunatha Reddy
Nachiketh P
Sumathra Manokaran
Abstract
3D printing or additive manufacturing (AM) is the process of constructing 3D models using computer aided manufacturing (CAD) or a digital 3D model. AM has the potential to democratize the production of goods and is driving innovations in many fields such as art, education, manufacturing, engineering and medicine. The innovations have led to 3D printing of biocompatible materials, cells and other structural components into complex 3D functional living tissues – known as 3D bioprinting. Various methods of 3D bioprinting are being researched to cater to specific needs. Bioinks are an important component of bioprinting, it consists of biomaterials that encapsulate cells and also adding biomolecules, many varieties of bioinks are available in the market and also developed based on the requirements. Although new approaches are being made there are certain key measures to face such as material properties, scaffold structures, printing precision, environmental control and sterile condition. Commercialization of bioprinters and its components has high potential to break market barriers and become a creative source of income. The applications of 3D bioprinting are vast including tissue engineering and regenerative medicine; transplantation and clinics; drug screening and high-throughput assays; and cancer research. There are many discrepancies that hinder the growth of 3D bioprinting and there are many approaches being researched on to solve those crises.
How to Cite
Reddy, M., Nachiketh P, & Manokaran, S. (2021). Overview of 3D Bioprinting of tissues and organs – A Review. SPAST Abstracts, 1(01). Retrieved from https://spast.org/techrep/article/view/1059
Article Details
Keywords
Bioprinting, Bioink, Tissue-Engineering, Computer Aided Manufacturing, Additive Manufacturing
References
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6. Gao, W., Y.B. Zhang, D. Ramanujan, et al. The status, challenges, and future of additive manufacturing in engineering. Computer-Aided Design. 2015; 69:65-89.
7. Mironov, V., V. Kasyanov, C. Drake, et al (2008), Organ printing: promises and challenges. Regenerative Medicine. 2008; 3(1):93-103.
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11. Mathew Varkey, Dafydd O. Visscher,Paul P. M. van Zuijlen,Anthony Atala & James J. Yoo. Skin bioprinting: the future of burn wound reconstruction?. Burns & Trauma. 2019; 7(4):
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15. Yong He, Zeming Gu, Mingjun Xie, Jianzhong Fu & Hui Lin. Why choose 3D bioprinting? Part II: methods and bioprinters. Bio-Design and Manufacturing 2020; volume 3, pages1–4 ,
16. Jones N. Science in three dimensions: the print revolution. Nature. 2012; 487(7405):22–23.
17. Iwanaga S, Arai K, Nakamura M. Inkjet bioprinting essentials of 3D biofabrication and translation. Elsevier, Amsterdam, pp 61–79, 2015.
18. Guillotin B, Ali M, Ducom A, Catros S, Keriquel V, Souquet A, Remy M, Fricain J-C, Guillemot F .Laser-assisted bioprinting for tissue engineering biofabrication. Elsevier, Amsterdam, pp 95–118, 2013.
19. Workman VL, Tezera LB, Elkington PT, Jayasinghe SN .Controlled generation of microspheres incorporating extracellular matrix fibrils for three-dimensional cell culture. Adv Funct Mater 2014; 24(18):2648–2657.
20. Gasperini L, Maniglio D, Migliaresi C .Microencapsulation of cells in alginate through an electrohydrodynamic process. J Bioact Compat Polym 2013; 28(5):413–425.
21. Klebe RJ .Cytoscribing: a method for micropositioning cells and the construction of two-and three-dimensional synthetic tissues. Exp Cell Res 1988; 179(2):362–373
22. S. Wüst, R. Müller and S. Hofmann, J. Funct. Biomater., 2011; 2, 119–154
23. H. J. Lee, Y. B. Kim, S. H. Ahn, J.-S. Lee, C. H. Jang, H. Yoon, W. Chun and G. H. Kim, Adv. Healthc. Mater., 2015; 4, 1359–1368.
24. Y. Loo, A. Lakshmanan, M. Ni, L. L. Toh, S. Wang and C. A. E. Hauser, Nano Lett., 2015; 15, 6919–6925.
25. D.-Y. Lee, H. Lee, Y. Kim, S. Y. Yoo, W.-J. Chung and G. Kim, Acta Biomater., 2016; 29, 112–124.
26. R. K. Bregg, Current Topics in Polymer Research, Nova Publishers, 2005.
27. Gungor-Ozkerim, P. Selcan; Biruni Universitesi, Biomedical Engineering Inci, Ilyas; Brigham and Women's Hospital, Department of Medicine Zhang, Y. Shrike; Harvard Medical School, Medicine Khademhosseini, Ali; Harvard-MIT, Division of Health Science and Technology Dokmeci, Mehmet; Harvard-MIT, Division of Health Science and Technology, Division of Engineering in Medicine. Bioinks for 3D Bioprinting: An Overview. Journal:Biomaterials Science. Review Article 21-Dec-2017.
28. K. Jakab, B. Damon, A. Neagu, A. Kachurin and G. Forgacs, Biorheology, 2006; 43, 509– 513.
29. A. Faulkner-Jones, S. Greenhough, J. A. King, J. Gardner, A. Courtney and W. Shu, Biofabrication, 2013; 5, 015013.
30. A. Skardal, J. Zhang, L. McCoard, S. Oottamasathien and G. D. Prestwich, Adv. Mater., 2010; 22, 4736–4740.
31. S. R. Shin, R. Farzad, A. Tamayol, V. Manoharan, P. Mostafalu, Y. S. Zhang, M. Akbari, S. M. Jung, D. Kim, M. Comotto, N. Annabi, F. E. Al-Hazmi, M. R. Dokmeci and A. Khademhosseini, Adv. Mater., 2016; 28, 3280–3289.
32. R. Goldman, Adv. Skin Wound Care, 2004; 17, 24–35.
33. L. Elowsson, H. Kirsebom, V. Carmignac, B. Mattiasson and M. Durbeej, Biomater. Sci., 2013; 1, 402–410.
34. M. Gruene, M. Pflaum, A. Deiwick, L. Koch, S. Schlie, C. Unger, M. Wilhelmi, A. Haverich and B. N. Chichkov, Biofabrication, 2011; 3, 015005.
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Section
NB:Biology