APPROVAL JOURNEY OF FAVIPIRAVIR FOR COVID-19
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Abstract
From all over the world, 16 million cases have been reported till now and counting the SARS-CoV-2, a minute 125 microns in diameter, has left an ineradicable impact throughout the globe. With the scarcity of new drugs to overcome this disease, the medical fraternity is in rush to find out repurposed drugs that may be effectual against the novel coronavirus. Recently one of the drugs has gained much emphasis, mainly in India, is an anti-viral drug called favipiravir which was originally designed for influenza. So here in this study, we tried to cover a complete, evidence-based review for favipiravir related to the present pandemic condition to illuminate its role in the COVID-19 management. We have covered pharmacology, pharmacokinetics, pharmacodynamics, its mechanism of action. It works by undergoing phosphoribosylation within the tissue. It shows its antiviral properties. We have covered the role of favipiravir in SARS-COV-2. Ongoing trials in India, Saudi Arabia, Russia, USA has also been discussed along with the adverse effects of the drug, and its dosing regimen.
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COVID-19, favipiravir, antiviral drug.
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